心臟血管用藥上一頁
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藥名╱含量 |
給藥途徑* |
稀釋液** |
每瓶稀釋液體積 |
給藥濃度 |
給藥速率 |
注意事項 |
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Amiodarone HCl Cordaroneâ150mg/3ml/amp |
IF4 |
D5W4 |
250-500ml /2amp4 |
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20min-2hr4 |
·注射間隔15分鐘後，才可注射第二劑4 ·IV> 30sec: FDA未核准1 |
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Atropine Sulfate Atropine Ò 1mg/1ml/amp |
IV2 |
undiluted |
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·不建議IF或加入其他點滴液一起輸注 |
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IM2 SC2 |
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Digoxin Digosinâ 0.25mg/1ml/amp Lanoxinâ0.5mg/2ml/A
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IV2 |
undiluted or diluted with W, D5W, NS2 |
³4倍體積 |
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³1-5min2 |
·IM: 非常痛，除非不能IV，不要用此途徑2 |
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Dipyridamole Persantinâ 10mg/2ml/amp (常備藥，僅供診斷用) |
IF 3,5 |
D5W, NS 0.45%/NaCl 3, 4, 5 |
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＜5mg/ml 5 |
0.142 mg/kg/min over 4 min 3, 4, 5 with thallium myo- cardial perfusion imaging |
·與diluent以至少1:2比例稀釋至20-50 ml 3, 5 ·注射未稀釋藥品會引起靜脈刺激 3, 5 |
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Dobutamine HCl Dobutrex Ò 250mg/20mL/vial Utamine Ò |
IF |
NS, D5W1 |
50-1000 mL1 |
250-5000 mcg/mL1 |
Ad. 2-20 mcg/kg/min1 Ch. 2-7.7mcg/kg/min5 |
· Stability after reconstitution: 6hr at RT and under refrigeration 48hr. Soln for IF should be used within 24hr |
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Dopamine HCl Dopamine Ò, Intropin Ò 200mg/5mL/amp
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IF |
D5W, NS, LR4 |
125-500 mL4 |
400-1600 mcg/mL4 |
Ad. Shock 2-20 mcg/kg/min Max.50mcg/kg/min1 Refractory CHF 0.5-2 mcg/kg/min, Max.3mcg/kg/min1 Ch.0.3-25 mcg/kg/min 5 |
· If extravasation happened, infiltrate this ischemic area with 10-15mL NS + phentolamine SC. immediately4 |
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Epinephrine HCl (Adrenaline HCl) Bosmin Ò 1mg/1mL/amp 1:1000
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IV |
W, NS |
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100mcg/mL |
Anaphylaxis Ad: 0.1-0.25mg over 5-10 min Ch:LD<0.1mg over 5-10 min |
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IF |
D5W |
250mL |
4mcg/mL |
Anaphylaxis Ch: 0.1mcg/kg/min, Max 1.5mcg/kg/min Asthma 1mcg/min, Max. 4 mcg/min
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Bradycardia Ad: initial 1mcg/min; then 1-10 mcg/min Ch: 0.1mcg/kg/min, Max 1mcg/kg/min 1 |
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Esmolol HCl BreviblocÒ 100 mg/10ml/vial |
IF |
undiluted |
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10mg/ml |
loading : 0.5mg/kg/min for 1 minute or 1mg /kg over 30 seconds 1 maintenance : 0.05-0.3mg/kg/min1 |
IF濃度20mg/ml靜脈刺激較嚴重
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Furosemide LasixÒ 20mg/2ml/amp Rasitol® 20mg/2ml/amp SuopinchonÒ |
IV |
undiluted |
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10mg/ml |
over 1-2min1 |
·同樣劑量，24小時continuous IF比bolus injection有效 ·避光，若變黃色，勿使用2 ·室溫下貯存，勿冷藏以免沈澱，但回溫後可溶解而不影響其穩定性2 ·忌酸性溶液，必要時可以NS, LR, D5W調整pH值，使pH³5.51,5 ·不可與GM, netilmicin, milrinone混合，以免沈澱5 |
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IF |
NS, LR, D5W(pH³5.5) |
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£4mg/min1 (adult) |
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Glycerin , Glycetoseâ Glyceolâ 10% 500ml/btl (+ 5% fructose& N/S) |
IF |
undiluted |
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125ml/hr |
·輸注過速可能造成溶血。 |
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藥名╱含量 |
給藥途徑* |
稀釋液** |
每瓶稀釋液體積 |
給藥濃度 |
給藥速率 |
注意事項 |
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Hydralazine HCl ApresolineÒ 20mg/amp |
IM1,2 |
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·忌以dextrose溶液稀釋。 ·會與一些金屬產生反應而變色 ·勿冷藏 ·8-12小時內點滴液顏色改變，不影響效價1,2。 ·IF應用syringe pump. |
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IV |
W（馬上使用） |
1ml |
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IF |
W1ml ,then NS |
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Labetalol HCl TrandateÒ 25 mg/5ml/amp |
IV |
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> 2min |
·點滴速率依血壓反應來調整 |
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Continuous IF |
D5W,NS,LR |
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1mg/ml1 |
2 mg/min |
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Mannitol Mannitol Ò 20% 300ml/bot |
IF only ·oliguria: |
undiluted
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50-100g over > 1.5 hr1,2 |
·應使用有filter之infusion set ·如有結晶可用60-80°C水浴，定期用力振搖，直到溶解，返回體溫後再使用 |
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·reduce intracranial pressure: |
1.5-2g/kg over 30-60min |
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·edema and ascites: |
100mg over 2-6hr |
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·measure GFR: |
NS |
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100ml 20% soln / 280ml NS |
20ml/min |
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Nitroglycerin (Glyceryl Trinitrate ) Tridil Ò 50mg/10mL/amp NitroglycerinÒ 50mg/10mL/vial MillisrolÒ 5mg/10mL/amp
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IF |
D5W, NS |
125-500 mL/50mg |
< 400 mcg/mL |
Ad: 5mcg/min by 5mcg/min q3-5min, up to 20mcg/min. If no responses, 10-20mcg/min to desired effect or appearance of headache or nausea. Max. 100mcg/min.1 Ch: 0.25-0.5 mcg/kg/min or 5mcg/min, whichever is less. Max. 5mcg/kg/min not to exceed adult dose. |
·Non-PVC tubing is recommended, as PVC absorb 40-80% NTG. ·Stability after reconstitution: 2days at RT, 7days under refrigeration. |
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藥名╱含量 |
給藥途徑* |
稀釋液** |
每瓶稀釋液體積 |
給藥濃度 |
給藥速率 |
注意事項 |
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Pentoxifylline Trentalâ ,Pentoxillineâ 100mg/5ml/amp |
IV |
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< 20mg/min4 |
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IF(preferred ) 4 |
D5W, NS4, LR |
125-250ml 4 |
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over 2-3hr |
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IA4 |
NS4 |
20-50ml 4 |
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10mg/min4 |
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Verapamil HCl Isoptin® 5mg/2ml/amp Verpamil® 5mg/2ml/amp |
Slow IV |
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Adult: over ³2min Children: over ³ 5min4 Elderly: over ³ 3min |
·Daily IV max dose 100mg4 |
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IF（不建議）1 |
D5W4, NS |
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5-10mg/hr4 |
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Diltiazem Herbesserâ 10mg/amp
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Slow IV, |
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over ³2min |
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IF |
D5W, NS |
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5-15ug/kg/min |
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